学術論文

セラミド基盤研究

2023

Chain length of covalently bound ceramides correlates with skin barrier function in healthy subjects

Journal of Dermatological Science2023,110,1, 35-38

2005

Characterization of surfactant-induced skin damage through barrier recovery induced by pseudoacylceramides

Dermatology Vol.211, No.2, 128-134

2004

Reevaluation of the importance of barrier dysfunction in the nonlesional dry skin of atopic dermatitis patients through the use of two barrier creams

Exogenous Dermatology Vol.3, No.6, 293-302

2004

Surfactant-induced depletion of ceramides and other intercellular lipids: Implication for the mechanism leading to dehydration of the stratum corneum

Exogenous Dermatology Vol.3, No.2, 81-98

2004

Decreased levels of covalently bound ceramide are associated with ultraviolet B-induced perturbation of the skin barrier

Journal of Investigative Dermatology Vol.123, No.6, 1102-1109

1991

Stratum corneum lipids serve as a bound-water modulator

Journal of Investigative Dermatology Vol.96, No.6, 845-851

1991

Decreased level of ceramides in stratum corneum of atopic dermatitis: An etiologic factor in atopic dry skin?

Journal of Investigative Dermatology Vol.96, No.4, 523-526

1989

Functions of lipids on human skin

Journal of Dispersion Science and Technology Vol.10, No.4-5, 617-641

1989

Water-retaining function in the stratum corneum and its recovery properties by synthetic pseudoceramides

Journal of the Society of Cosmetic Chemists Vol.40, No.5, 273-285

1989

Importance of intercellular lipids in water-retention properties of the stratum corneum: induction and recovery study of surfactant dry skin

Arch Dermatol Res Vol.281, No.1, 45-51

1986

Selective recovery of deranged water-holding properties by stratum corneum lipids

Journal of Investigative Dermatology Vol.87, No.6, 758-761

1985

A possible function of structural lipids in the water-holding properties of the stratum corneum

Journal of Investigative Dermatology Vol.84, No.4, 282-4

セラミド・敏感肌基盤研究

2023

「第24回マルホ研究賞」受賞

2022

Stratum Corneum Ceramide Profiles Provide Reliable Indicators of Remission and Potential Flares in Atopic Dermatitis

Journal of Investigative Dermatology Vol.142、No.12、3184-3191.

2022

Effects of a moisturizer containing pseudo-ceramide and a eucalyptus extract on sweating function in adult atopic dermatitis: a double-blind, randomized, controlled left-right comparison clinical trial

Journal of Cosmetic Dermatology Vol.21、No.10、4503-4509.

2020

The ceramide [NP]/[NS] ratio in the stratum corneum is a potential marker for skin properties and epidermal differentiation

BMC Dermatology Vol.20, No.6

2020

Treatment with Synthetic Pseudoceramide Improves Atopic Skin, Switching the Ceramide Profile to a Healthy Skin Phenotype

Journal of Investigative Dermatology Vol.140, No.9, 1762-1770

2019

UVB sensitivity correlates with cutaneous barrier function in the skin of Japanese females

Photoderm Photoimmunol Photomed Vol.35, No.4, 284-285

2013

Dry skin in the winter is related to the ceramide profile in the stratum corneum and can be improved by treatment with a Eucalyptus extract

Journal of Cosmetic Dermatology Vol.12, No.1, 3-11

2012

Eucalyptus increases ceramide levels in keratinocytes and improves stratum corneum function

International Journal of Cosmetic Science Vol.34, No.1, 17-22

2010

Comparison of skin barrier function and sensory nerve electric current perception threshold between IgE-high extrinsic and IgE-normal intrinsic types of atopic dermatitis

British Journal of Dermatology Vol.162, No.1, 83-90

2010

Changes in the ceramide profile of atopic dermatitis patients

Journal of Investigative Dermatology Vol.130, No.10, 2511-2514

2009

Comprehensive quantification of ceramide species in human stratum corneum

Journal of Lipid Research Vol.50, No.8, 1708-1719

2008

Characterization of overall ceramide species in human stratum corneum

Journal of Lipid Research Vol.49, No.7, 1466-1476

セラミド機能成分*クリニカルユーステスト
*ヘキサデシロキシPGヒドロキシエチルヘキサデカナミド

2022

Usefulness of a synthetic ceramide containing moisturizing spray to maintain remission of atopic dermatitis

Aesthetic Dermatology Vol.32:18-27,2022

2022

Washing with a body cleanser and topical application of a moisturizer containing a pseudo-ceramide and a eucalyptus extract are effective to improve mild atopic dermatitis in Thailand

J. Cosmet Dermatol. 2022;21,6443–6445.   

2021

Rubbing the skin when removing makeup cosmetics is a major factor that worsens skin conditions in atopic dermatitis Patients

J Cosmet Dermatol. Vol.20, 1915–1922

2021

The efficacy of synthetic pseudo-ceramide for dry and rough lips

International Journal of Cosmetic Science, Vol.43, 158–164

2020

擬似セラミドをラメラ状にして配合したクリームのアトピー性皮膚炎患者に対する有用性評価

Aesthetic Dermatology Vol.30, No.3, 261-270

2019

Efficacy of a moisturizer containing a pseudo-ceramide and a eucalyptus extract for Japanese patients with mild atopic dermatitis in the summer

Journal of Cosmetic Dermatology Vol.18, No.3, 850-856

2018

The efficacy of a lip balm containing pseudo-ceramide on the dry lips of sensitive skin-conscious subjects

Journal of Cosmetic Dermatology Vol.17, No.1, 84-89

2018

The efficacy of a pseudo-ceramide and eucalyptus extract containing lotion on dry scalp skin

Clinical, Cosmetic and Investigational Dermatology Vol.11, 141-148

2018

Amelioration of lactic acid sensations in sensitive skin by stimulating the barrier function and improving the ceramide profile

Archives of Dermatological Research Vol.310, No.6, 495-504

2017

Subclinical cutaneous inflammation remained after permeability barrier disruption enhances UV sensitivity by altering ER stress responses and topical pseudoceramide prevents them

Archives of Dermatological Research Vol.309, No.7, 541-550

2015

Efficacy of the combined use of a facial cleanser and moisturizers for the care of mild acne patients with sensitive skin

Journal of Dermatology Vol.42, No.2, 181-188

2014

Evaluation of a Pseudoceramide Moisturizer in Patients with Mild-to-Moderate Atopic Dermatitis

Dermatol Ther (Heidelb) Vol.4, No.1, 83–92

2011

Pseudo-ceramide for childhood eczema: does it work?

Hong Kong Medical Journal Vol.17, No.2, 132-136

2009

Efficacy and safety of pseudo-ceramide containing moisture cream in the treatment of senile xerosis

Hong Kong Journal of Dermatology and Venereology Vol.17, No.4, 181-184

2006

アトピックドライスキンにおけるバリアー障害の回復の意義

西日皮膚 Vol.68, No.4, 413-421

2004

Recharacterization of the nonlesional dry skin in atopic dermatitis through disrupted barrier function

Exogenous Dermatology Vol.3, No.6, 282-292

2004

新生児・乳幼児に対するスキンケア及び洗浄製品の使用試験

日本小児皮膚科学会誌 Vol.23, No.2, 247-258

2004

合成擬似セラミド配合全身ローション(KO401)の有用性と安全性の検討

臨牀と研究 Vol.81, No.12, 2039-2049

2002

アトピー性皮膚炎に対する合成疑似セラミド含有クリームの有用性の検討 —尿素含有クリームとの比較—

西日本皮膚科 Vol.64, No.5, 606-611

2001

アトピー性皮膚炎患者に対する合成擬似セラミド含有クリームの有用性の検討

西日本皮膚科 Vol.4, No.63, 457-461

2000

アトピックドライスキンに対するスキンケア製品の使用経験

皮膚別冊 Vol.42, No.2, 264-269

1999

アトピー性皮膚炎患者に対する合成擬似セラミドクリームの有用性および安全性の検討

西日本皮膚 Vol.61, No.5, 671-681

総説その他

総説

2021

乾燥に起因するかゆみに対する保湿剤の有用性-皮膚バリア機能改善とセラミドプロファイルの変化

フレグランスジャーナル 49 (12) 32-38, 2021.

2021

乾燥皮膚のかゆみに対するスキンケア保湿剤の有用性

Medical Science Digest Vol 47, No.4, Industry News

2021

セラミドに着目した敏感肌のスキンケア

日本香粧品学会誌 Vol45, No3, 201-208

2021

角層バリア機能の紫外線感受性に対する影響ーセラミドケアによる紫外線防御ー

進化する皮膚科学(株式会社エヌ・ティー・エス)pp.341-349

2020

マイクロミキサーで混ぜる -ミリ秒高速混合を利用した新規ナノ乳化技術

化学と工業 Vol.73, No.5, 405-407

2016

敏感肌とは何か?

Bella Pelle Vo.1, No.2, 90-93

2011

敏感肌ー意識・実態とスティンギング(刺激感)

日本香粧品学会誌 Vo.35, No.2, 107-112

2011

ヒト角層・毛髪におけるセラミド分子網羅解析技術の開発

フレグランスジャーナル No.7、17-24

2011

アトピー性皮膚炎におけるセラミドケアの重要性(2)

アレルギーの臨床 Vol.31, No.2, 60-66

2010

アトピー性皮膚炎におけるセラミドケアの重要性

アレルギーの臨床 Vol.30, No.13, 50-55

2007

保湿のメカニズムと頭皮ケア

皮膚と美容 Vol.39, No.4, 214-9

2006

こどものスキンケア -スキンケア製品

小児看護 Vol.29, No.10, 1355-1378

2006

化粧品の機能について 敏感肌用化粧品

Visual Dermatology Vol.5, No.5, 442-445

2005

アトピー性皮膚炎患者と対象とした化粧品の効用

Visual Dermatology Vol.4, No.12, 1224-1225

著書(共著):本の一章

2015

Atopic dermatitis (AD) and lipids

Lipids and Skin Health pp.343-356

2001

Ceramides as natural moisturizing factors and their efficacy in dry skin

Skin Moisturization pp.267-302
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